Global phosphoproteomics reveals DYRK1A regulates CDK1 activity in glioblastoma cells
Global phosphoproteomics reveals DYRK1A regulates CDK1 activity in glioblastoma cells
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Both tumour suppressive and oncogenic functions have been reported for dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A). Herein, we performed a detailed investigation to delineate the role of DYRK1A in glioblastoma. Our phosphoproteomic and mechanistic studies show that DYRK1A induces degradation of cyclin B by phosphorylating...
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Global phosphoproteomics reveals DYRK1A regulates CDK1 activity in glioblastoma cells
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TN_cdi_doaj_primary_oai_doaj_org_article_0a8dca1bb09e4683a7fb6162b88375d9
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0a8dca1bb09e4683a7fb6162b88375d9
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ISSN
2058-7716
E-ISSN
2058-7716
DOI
10.1038/s41420-021-00456-6
