Reversal of pre-existing NGFR-driven tumor and immune therapy resistance
Reversal of pre-existing NGFR-driven tumor and immune therapy resistance
About this item
Full title
Author / Creator
Boshuizen, Julia , Vredevoogd, David W. , Krijgsman, Oscar , Ligtenberg, Maarten A. , Blankenstein, Stephanie , de Bruijn, Beaunelle , Frederick, Dennie T. , Kenski, Juliana C. N. , Parren, Mara , Brüggemann, Marieke , Madu, Max F. , Rozeman, Elisa A. , Song, Ji-Ying , Horlings, Hugo M. , Blank, Christian U. , van Akkooi, Alexander C. J. , Flaherty, Keith T. , Boland, Genevieve M. and Peeper, Daniel S.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Melanomas can switch to a dedifferentiated cell state upon exposure to cytotoxic T cells. However, it is unclear whether such tumor cells pre-exist in patients and whether they can be resensitized to immunotherapy. Here, we chronically expose (patient-derived) melanoma cell lines to differentiation antigen-specific cytotoxic T cells and observe str...
Alternative Titles
Full title
Reversal of pre-existing NGFR-driven tumor and immune therapy resistance
Authors, Artists and Contributors
Author / Creator
Vredevoogd, David W.
Krijgsman, Oscar
Ligtenberg, Maarten A.
Blankenstein, Stephanie
de Bruijn, Beaunelle
Frederick, Dennie T.
Kenski, Juliana C. N.
Parren, Mara
Brüggemann, Marieke
Madu, Max F.
Rozeman, Elisa A.
Song, Ji-Ying
Horlings, Hugo M.
Blank, Christian U.
van Akkooi, Alexander C. J.
Flaherty, Keith T.
Boland, Genevieve M.
Peeper, Daniel S.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_0aa2077077d243cb9f117c28a0c8e4f1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0aa2077077d243cb9f117c28a0c8e4f1
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-17739-8
