CXCL12 modulation of CXCR4 and CXCR7 activity in human glioblastoma stem-like cells and regulation o...
CXCL12 modulation of CXCR4 and CXCR7 activity in human glioblastoma stem-like cells and regulation of the tumor microenvironment
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Publisher
Switzerland: Frontiers Research Foundation
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Language
English
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Publisher
Switzerland: Frontiers Research Foundation
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Contents
Chemokines are crucial autocrine and paracrine players in tumor development. In particular, CXCL12, through its receptors CXCR4 and CXCR7, affects tumor progression by controlling cancer cell survival, proliferation and migration, and, indirectly, via angiogenesis or recruiting immune cells. Glioblastoma (GBM) is the most prevalent primary malignan...
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Full title
CXCL12 modulation of CXCR4 and CXCR7 activity in human glioblastoma stem-like cells and regulation of the tumor microenvironment
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TN_cdi_doaj_primary_oai_doaj_org_article_0ab2abd99c234ef5adac352e9ce5ab13
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0ab2abd99c234ef5adac352e9ce5ab13
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ISSN
1662-5102
E-ISSN
1662-5102
DOI
10.3389/fncel.2014.00144
