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Helper NLR immune protein NRC3 evolved to evade inhibition by a cyst nematode virulence effector

Helper NLR immune protein NRC3 evolved to evade inhibition by a cyst nematode virulence effector

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0acd8e79643d4476910a654697438bae

Helper NLR immune protein NRC3 evolved to evade inhibition by a cyst nematode virulence effector

About this item

Full title

Helper NLR immune protein NRC3 evolved to evade inhibition by a cyst nematode virulence effector

Publisher

United States: Public Library of Science

Journal title

PLoS genetics, 2025-04, Vol.21 (4), p.e1011653

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Parasites can counteract host immunity by suppressing nucleotide binding and leucine-rich repeat (NLR) proteins that function as immune receptors. We previously showed that a cyst nematode virulence effector SPRYSEC15 (SS15) binds and inhibits oligomerisation of helper NLR proteins in the expanded NRC1/2/3 clade by preventing intramolecular rearran...

Alternative Titles

Full title

Helper NLR immune protein NRC3 evolved to evade inhibition by a cyst nematode virulence effector

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_0acd8e79643d4476910a654697438bae

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0acd8e79643d4476910a654697438bae

Other Identifiers

ISSN

1553-7404,1553-7390

E-ISSN

1553-7404

DOI

10.1371/journal.pgen.1011653

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