Single-Cell Virology: On-Chip, Quantitative Characterization of the Dynamics of Virus Spread from On...
Single-Cell Virology: On-Chip, Quantitative Characterization of the Dynamics of Virus Spread from One Single Cell to Another
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Publisher
Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Contents
Virus spread at the single-cell level is largely uncharacterized. We have designed and constructed a microfluidic device in which each nanowell contains a single, infected cell (donor) and a single, uninfected cell (recipient). Using a GFP-expressing poliovirus as our model, we observed both lytic and non-lytic spread. Donor cells supporting lytic...
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Full title
Single-Cell Virology: On-Chip, Quantitative Characterization of the Dynamics of Virus Spread from One Single Cell to Another
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TN_cdi_doaj_primary_oai_doaj_org_article_0b6f3ebd79454b09a31c81f579faa202
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0b6f3ebd79454b09a31c81f579faa202
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ISSN
1999-4915
E-ISSN
1999-4915
DOI
10.3390/v16111659
