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Phase 1 study of isatuximab monotherapy in Chinese patients with relapsed/refractory multiple myelom...

Phase 1 study of isatuximab monotherapy in Chinese patients with relapsed/refractory multiple myelom...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0b895c9da45f42e38c4d68e5d4bc73e9

Phase 1 study of isatuximab monotherapy in Chinese patients with relapsed/refractory multiple myeloma

About this item

Full title

Phase 1 study of isatuximab monotherapy in Chinese patients with relapsed/refractory multiple myeloma

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2024-11, Vol.14 (1), p.27550-9, Article 27550

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

In this multi-center, Phase-1 study (NCT03733717), we characterized the pharmacokinetics (PK) of the anti-CD38 antibody isatuximab (Isa) after IV administration (primary objective), and evaluated safety, immunogenicity, and preliminary anti-myeloma activity in Chinese patients with relapsed/refractory multiple myeloma (RRMM). Isa 20-mg/kg was admin...

Alternative Titles

Full title

Phase 1 study of isatuximab monotherapy in Chinese patients with relapsed/refractory multiple myeloma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_0b895c9da45f42e38c4d68e5d4bc73e9

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0b895c9da45f42e38c4d68e5d4bc73e9

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-024-59186-1

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