HTR1D regulates the PI3K/Akt signaling pathway to impact hepatocellular carcinoma development and re...
HTR1D regulates the PI3K/Akt signaling pathway to impact hepatocellular carcinoma development and resistance to sorafenib
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Hepatocellular carcinoma (HCC) has a poor prognosis, partly due to resistance to treatments like sorafenib. The 5-hydroxytryptamine receptor 1D (HTR1D) is involved in cancer progression through the PI3K/Akt pathway, but its role in HCC is not well understood. This study investigates HTR1D's expression, function, and potential as a prognostic marker...
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HTR1D regulates the PI3K/Akt signaling pathway to impact hepatocellular carcinoma development and resistance to sorafenib
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TN_cdi_doaj_primary_oai_doaj_org_article_0b97ac8816cb4e7cb7a2b996c0c3143e
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0b97ac8816cb4e7cb7a2b996c0c3143e
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ISSN
1471-2407
E-ISSN
1471-2407
DOI
10.1186/s12885-025-13575-5
