Aluminum fluoride-18 labeled folate enables in vivo detection of atherosclerotic plaque inflammation...
Aluminum fluoride-18 labeled folate enables in vivo detection of atherosclerotic plaque inflammation by positron emission tomography
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Silvola, Johanna M. U. , Li, Xiang-Guo , Virta, Jenni , Marjamäki, Päivi , Liljenbäck, Heidi , Hytönen, Jarkko P. , Tarkia, Miikka , Saunavaara, Virva , Hurme, Saija , Palani, Senthil , Hakovirta, Harri , Ylä-Herttuala, Seppo , Saukko, Pekka , Chen, Qingshou , Low, Philip S. , Knuuti, Juhani , Saraste, Antti and Roivainen, Anne
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Inflammation plays an important role in the development of atherosclerosis and its complications. Because the folate receptor β (FR-β) is selectively expressed on macrophages, an FR targeted imaging agent could be useful for assessment of atherosclerotic inflammation. We investigated aluminum fluoride-18-labeled 1,4,7-triazacyclononane-1,4,7-triace...
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Aluminum fluoride-18 labeled folate enables in vivo detection of atherosclerotic plaque inflammation by positron emission tomography
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TN_cdi_doaj_primary_oai_doaj_org_article_0ba0ded919c04de1bea8c1128f7cd5be
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0ba0ded919c04de1bea8c1128f7cd5be
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-018-27618-4