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Redox regulation of KV7 channels through EF3 hand of calmodulin

Redox regulation of KV7 channels through EF3 hand of calmodulin

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0bd7d7f107f1445e8d187383cd53a107

Redox regulation of KV7 channels through EF3 hand of calmodulin

About this item

Full title

Redox regulation of KV7 channels through EF3 hand of calmodulin

Publisher

eLife Sciences Publications, Ltd

Journal title

eLife, 2023-02, Vol.12

Language

English

Formats

Publication information

Publisher

eLife Sciences Publications, Ltd

More information

Scope and Contents

Contents

Neuronal K
V
7 channels, important regulators of cell excitability, are among the most sensitive proteins to reactive oxygen species. The S2S3 linker of the voltage sensor was reported as a site-mediating redox modulation of the channels. Recent structural insights reveal potential interactions between this linker and the Ca
2+
-binding...

Alternative Titles

Full title

Redox regulation of KV7 channels through EF3 hand of calmodulin

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_0bd7d7f107f1445e8d187383cd53a107

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0bd7d7f107f1445e8d187383cd53a107

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.81961

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