Transcriptome analysis of liver injury of fatty liver disease induced by ALDH2 deficiency
Transcriptome analysis of liver injury of fatty liver disease induced by ALDH2 deficiency
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Author / Creator
Xu, Ziying , Gao, Yagang , Yu, Zihui , Zhang, Rui , Wang, Ruikun , Li, Shang , Wang, Shuowen , Du, Bing , Tian, Ziyan , Huang, Lijuan , Ding, Zanbo and Yuan, Jing
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Aldehyde dehydrogenase 2 (
Aldh2
) Glu504Lys mutation, common in East Asians, is linked to various alcohol-related pathologies, notably fatty liver disease. Recent findings suggest that high ethanol-producing Klebsiella
pneumoniae
(HiAlc
Kpn
) exacerbates liver injury in non-alcoholic fatty liver disease (NAFLD). Our study investi...
Alternative Titles
Full title
Transcriptome analysis of liver injury of fatty liver disease induced by ALDH2 deficiency
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TN_cdi_doaj_primary_oai_doaj_org_article_0bd91be38dcd4b52aab144578c8c3295
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0bd91be38dcd4b52aab144578c8c3295
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-025-86547-1