Deciphering the exact breakpoints of structural variations using long sequencing reads with DeBreak
Deciphering the exact breakpoints of structural variations using long sequencing reads with DeBreak
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Long-read sequencing has demonstrated great potential for characterizing all types of structural variations (SVs). However, existing algorithms have insufficient sensitivity and precision. To address these limitations, we present DeBreak, a computational method for comprehensive and accurate SV discovery. Based on alignment results, DeBreak employs...
Alternative Titles
Full title
Deciphering the exact breakpoints of structural variations using long sequencing reads with DeBreak
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_0c0c45a0c4e04912a8a288fdeae3051d
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0c0c45a0c4e04912a8a288fdeae3051d
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-35996-1
