Cerebrospinal fluid profile of NPTX2 supports role of Alzheimer’s disease-related inhibitory circuit...
Cerebrospinal fluid profile of NPTX2 supports role of Alzheimer’s disease-related inhibitory circuit dysfunction in adults with Down syndrome
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Author / Creator
Belbin, Olivia , Xiao, Mei-Fang , Xu, Desheng , Carmona-Iragui, Maria , Pegueroles, Jordi , Benejam, Bessy , Videla, Laura , Fernández, Susana , Barroeta, Isabel , Nuñez-Llaves, Raúl , Montal, Victor , Vilaplana, Eduard , Altuna, Miren , Clarimón, Jordi , Alcolea, Daniel , Blesa, Rafael , Lleó, Alberto , Worley, Paul F. and Fortea, Juan
Publisher
London: BioMed Central Ltd
Journal title
Language
English
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Publisher
London: BioMed Central Ltd
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Scope and Contents
Contents
Background Alzheimer's disease (AD) is the major cause of death in adults with Down syndrome (DS). There is an urgent need for objective markers of AD in the DS population to improve early diagnosis and monitor disease progression. NPTX2 has recently emerged as a promising cerebrospinal fluid (CSF) biomarker of Alzheimer-related inhibitory circuit...
Alternative Titles
Full title
Cerebrospinal fluid profile of NPTX2 supports role of Alzheimer’s disease-related inhibitory circuit dysfunction in adults with Down syndrome
Authors, Artists and Contributors
Author / Creator
Xiao, Mei-Fang
Xu, Desheng
Carmona-Iragui, Maria
Pegueroles, Jordi
Benejam, Bessy
Videla, Laura
Fernández, Susana
Barroeta, Isabel
Nuñez-Llaves, Raúl
Montal, Victor
Vilaplana, Eduard
Altuna, Miren
Clarimón, Jordi
Alcolea, Daniel
Blesa, Rafael
Lleó, Alberto
Worley, Paul F.
Fortea, Juan
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_0c1c43d3ccb644e492a07268b4f71135
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0c1c43d3ccb644e492a07268b4f71135
Other Identifiers
ISSN
1750-1326
E-ISSN
1750-1326
DOI
10.1186/s13024-020-00398-0