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Combined impact of lipidomic and genetic aberrations on clinical outcomes in metastatic castration-r...

Combined impact of lipidomic and genetic aberrations on clinical outcomes in metastatic castration-r...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0c49ff062a1c4a14adec64ab46d60c0a

Combined impact of lipidomic and genetic aberrations on clinical outcomes in metastatic castration-resistant prostate cancer

About this item

Full title

Combined impact of lipidomic and genetic aberrations on clinical outcomes in metastatic castration-resistant prostate cancer

Publisher

England: BioMed Central Ltd

Journal title

BMC medicine, 2022-03, Vol.20 (1), p.112-14, Article 112

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Both changes in circulating lipids represented by a validated poor prognostic 3-lipid signature (3LS) and somatic tumour genetic aberrations are individually associated with worse clinical outcomes in men with metastatic castration-resistant prostate cancer (mCRPC). A key question is how the lipid environment and the cancer genome are interrelated...

Alternative Titles

Full title

Combined impact of lipidomic and genetic aberrations on clinical outcomes in metastatic castration-resistant prostate cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_0c49ff062a1c4a14adec64ab46d60c0a

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0c49ff062a1c4a14adec64ab46d60c0a

Other Identifiers

ISSN

1741-7015

E-ISSN

1741-7015

DOI

10.1186/s12916-022-02298-0

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