Deciphering cell lineage specification of human lung adenocarcinoma with single-cell RNA sequencing
Deciphering cell lineage specification of human lung adenocarcinoma with single-cell RNA sequencing
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Author / Creator
Wang, Zhoufeng , Li, Zhe , Zhou, Kun , Wang, Chengdi , Jiang, Lili , Zhang, Li , Yang, Ying , Luo, Wenxin , Qiao, Wenliang , Wang, Gang , Ni, Yinyun , Dai, Shuiping , Guo, Tingting , Ji, Guiyi , Xu, Minjie , Liu, Yiying , Su, Zhixi , Che, Guowei and Li, Weimin
Publisher
London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Contents
Lung adenocarcinomas (LUAD) arise from precancerous lesions such as atypical adenomatous hyperplasia, which progress into adenocarcinoma in situ and minimally invasive adenocarcinoma, then finally into invasive adenocarcinoma. The cellular heterogeneity and molecular events underlying this stepwise progression remain unclear. In this study, we perf...
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Full title
Deciphering cell lineage specification of human lung adenocarcinoma with single-cell RNA sequencing
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TN_cdi_doaj_primary_oai_doaj_org_article_0c591a024d8f4eb4b166ebe45fe652aa
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0c591a024d8f4eb4b166ebe45fe652aa
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-26770-2