Accelerated functional brain aging in pre-clinical familial Alzheimer’s disease
Accelerated functional brain aging in pre-clinical familial Alzheimer’s disease
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Full title
Author / Creator
Gonneaud, Julie , Baria, Alex T. , Pichet Binette, Alexa , Gordon, Brian A. , Chhatwal, Jasmeer P. , Cruchaga, Carlos , Jucker, Mathias , Levin, Johannes , Salloway, Stephen , Farlow, Martin , Gauthier, Serge , Benzinger, Tammie L. S. , Morris, John C. , Bateman, Randall J. , Breitner, John C. S. , Poirier, Judes , Vachon-Presseau, Etienne , Villeneuve, Sylvia , Alzheimer’s Disease Neuroimaging Initiative (ADNI) , Dominantly Inherited Alzheimer Network (DIAN) Study Group and Pre-symptomatic Evaluation of Experimental or Novel Treatments for Alzheimer’s Disease (PREVENT-AD) Research Group
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Resting state functional connectivity (rs-fMRI) is impaired early in persons who subsequently develop Alzheimer’s disease (AD) dementia. This impairment may be leveraged to aid investigation of the pre-clinical phase of AD. We developed a model that predicts brain age from resting state (rs)-fMRI data, and assessed whether genetic determinants of A...
Alternative Titles
Full title
Accelerated functional brain aging in pre-clinical familial Alzheimer’s disease
Authors, Artists and Contributors
Author / Creator
Baria, Alex T.
Pichet Binette, Alexa
Gordon, Brian A.
Chhatwal, Jasmeer P.
Cruchaga, Carlos
Jucker, Mathias
Levin, Johannes
Salloway, Stephen
Farlow, Martin
Gauthier, Serge
Benzinger, Tammie L. S.
Morris, John C.
Bateman, Randall J.
Breitner, John C. S.
Poirier, Judes
Vachon-Presseau, Etienne
Villeneuve, Sylvia
Alzheimer’s Disease Neuroimaging Initiative (ADNI)
Dominantly Inherited Alzheimer Network (DIAN) Study Group
Pre-symptomatic Evaluation of Experimental or Novel Treatments for Alzheimer’s Disease (PREVENT-AD) Research Group
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_0c59d82b7ea64e8e9da8283d5d2f0d76
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0c59d82b7ea64e8e9da8283d5d2f0d76
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-25492-9
