Mutations in the PIK3C2B , ERBB3 , KIT , and MLH1 Genes and Their Relationship with Resistance to Te...
Mutations in the PIK3C2B , ERBB3 , KIT , and MLH1 Genes and Their Relationship with Resistance to Temozolomide in Patients with High-Grade Gliomas
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Switzerland: MDPI AG
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Language
English
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Switzerland: MDPI AG
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The treatment for patients with high-grade gliomas includes surgical resection of tumor, radiotherapy, and temozolomide chemotherapy. However, some patients do not respond to temozolomide due to a methylation reversal mechanism by the enzyme O
-methylguanine-DNA-methyltransferase (MGMT). In patients receiving treatment with temozolomide, this bi...
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Mutations in the PIK3C2B , ERBB3 , KIT , and MLH1 Genes and Their Relationship with Resistance to Temozolomide in Patients with High-Grade Gliomas
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TN_cdi_doaj_primary_oai_doaj_org_article_0c61c9c36e6946e3b9bf0a2fc1c76fe1
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0c61c9c36e6946e3b9bf0a2fc1c76fe1
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ISSN
2227-9059
E-ISSN
2227-9059
DOI
10.3390/biomedicines12122777
