Elimination of HIV-1-infected cells by broadly neutralizing antibodies
Elimination of HIV-1-infected cells by broadly neutralizing antibodies
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Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
The Fc region of HIV-1 Env-specific broadly neutralizing antibodies (bNAbs) is required for suppressing viraemia, through mechanisms which remain poorly understood. Here, we identify bNAbs that exert antibody-dependent cellular cytotoxicity (ADCC) in cell culture and kill HIV-1-infected lymphocytes through natural killer (NK) engagement. These anti...
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Full title
Elimination of HIV-1-infected cells by broadly neutralizing antibodies
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_0c92443559f14621a72a3877677ac63a
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0c92443559f14621a72a3877677ac63a
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms10844
