Small-Molecule SB216763-Loaded Microspheres Repair Peripheral Nerve Injury in Small Gap Tubulization
Small-Molecule SB216763-Loaded Microspheres Repair Peripheral Nerve Injury in Small Gap Tubulization
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Author / Creator
Rao, Feng , Yuan, Zhipeng , Zhang, Dianying , Yu, Fei , Li, Ming , Li, Dongdong , Jiang, Baoguo , Wen, Yongqiang and Zhang, Peixun
Publisher
Switzerland: Frontiers Research Foundation
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Language
English
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Publisher
Switzerland: Frontiers Research Foundation
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Contents
Peripheral nerve injury has yet to be fully resolved because of its complicated pathological process. SB216763 is a small molecular compound that can enhance the remyelination of peripheral nerves by inhibiting glycogen synthase kinase-3β (GSK3β). GSK-3β inhibitor stimulates myelin gene expression and restores the myelin structure. Herein, we prese...
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Full title
Small-Molecule SB216763-Loaded Microspheres Repair Peripheral Nerve Injury in Small Gap Tubulization
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TN_cdi_doaj_primary_oai_doaj_org_article_0cb0bf811cf94afaac70d08eca276acd
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0cb0bf811cf94afaac70d08eca276acd
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ISSN
1662-453X,1662-4548
E-ISSN
1662-453X
DOI
10.3389/fnins.2019.00489