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CB₂ receptor deficiency increases amyloid pathology and alters tau processing in a transgenic mouse...

CB₂ receptor deficiency increases amyloid pathology and alters tau processing in a transgenic mouse...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0d080a04a6a741f0bc8dc3db1667163b

CB₂ receptor deficiency increases amyloid pathology and alters tau processing in a transgenic mouse model of Alzheimer's disease

About this item

Full title

CB₂ receptor deficiency increases amyloid pathology and alters tau processing in a transgenic mouse model of Alzheimer's disease

Publisher

England: BioMed Central

Journal title

Molecular medicine (Cambridge, Mass.), 2013-01, Vol.19 (1), p.357-36

Language

English

Formats

Publication information

Publisher

England: BioMed Central

More information

Scope and Contents

Contents

The endocannabinoid CB₂ receptor system has been implicated in the neuropathology of Alzheimer's disease (AD). In order to investigate the impact of the CB₂ receptor system on AD pathology, a colony of mice with a deleted CB₂ receptor gene, CNR2, was established on a transgenic human mutant APP background for pathological comparison with CB₂ recept...

Alternative Titles

Full title

CB₂ receptor deficiency increases amyloid pathology and alters tau processing in a transgenic mouse model of Alzheimer's disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_0d080a04a6a741f0bc8dc3db1667163b

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0d080a04a6a741f0bc8dc3db1667163b

Other Identifiers

ISSN

1076-1551

E-ISSN

1528-3658

DOI

10.2119/molmed.2013.00140

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