Atg4 proteolytic activity can be inhibited by Atg1 phosphorylation
Atg4 proteolytic activity can be inhibited by Atg1 phosphorylation
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The biogenesis of autophagosomes depends on the conjugation of Atg8-like proteins with phosphatidylethanolamine. Atg8 processing by the cysteine protease Atg4 is required for its covalent linkage to phosphatidylethanolamine, but it is also necessary for Atg8 deconjugation from this lipid to release it from membranes. How these two cleavage steps ar...
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Atg4 proteolytic activity can be inhibited by Atg1 phosphorylation
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TN_cdi_doaj_primary_oai_doaj_org_article_0d25d8e1163b4f90ae02c9c439b13fba
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0d25d8e1163b4f90ae02c9c439b13fba
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-017-00302-3