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Atg4 proteolytic activity can be inhibited by Atg1 phosphorylation

Atg4 proteolytic activity can be inhibited by Atg1 phosphorylation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0d25d8e1163b4f90ae02c9c439b13fba

Atg4 proteolytic activity can be inhibited by Atg1 phosphorylation

About this item

Full title

Atg4 proteolytic activity can be inhibited by Atg1 phosphorylation

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2017-08, Vol.8 (1), p.295-10, Article 295

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The biogenesis of autophagosomes depends on the conjugation of Atg8-like proteins with phosphatidylethanolamine. Atg8 processing by the cysteine protease Atg4 is required for its covalent linkage to phosphatidylethanolamine, but it is also necessary for Atg8 deconjugation from this lipid to release it from membranes. How these two cleavage steps ar...

Alternative Titles

Full title

Atg4 proteolytic activity can be inhibited by Atg1 phosphorylation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_0d25d8e1163b4f90ae02c9c439b13fba

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0d25d8e1163b4f90ae02c9c439b13fba

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-017-00302-3

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