PKCα-mediated phosphorylation of LSD1 is required for presynaptic plasticity and hippocampal learnin...
PKCα-mediated phosphorylation of LSD1 is required for presynaptic plasticity and hippocampal learning and memory
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Lim, Chae-Seok , Nam, Hye Jin , Lee, Jaehyun , Kim, Dongha , Choi, Ja Eun , Kang, SukJae Joshua , Kim, Somi , Kim, Hyopil , Kwak, Chuljung , Shim, Kyu-Won , Kim, Siyong , Ko, Hyoung-Gon , Lee, Ro Un , Jang, Eun-Hae , Yoo, Juyoun , Shim, Jaehoon , Islam, Md Ariful , Lee, Yong-Seok , Lee, Jae-Hyung , Baek, Sung Hee and Kaang, Bong-Kiun
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Lysine-specific demethylase 1 (LSD1) is a histone demethylase that participates in transcriptional repression or activation. Recent studies reported that LSD1 is involved in learning and memory. Although LSD1 phosphorylation by PKCα was implicated in circadian rhythmicity, the importance of LSD1 phosphorylation in learning and memory is unknown. In...
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PKCα-mediated phosphorylation of LSD1 is required for presynaptic plasticity and hippocampal learning and memory
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TN_cdi_doaj_primary_oai_doaj_org_article_0d31f3b5d7f647abb2626298419871e9
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0d31f3b5d7f647abb2626298419871e9
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-017-05239-7
