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Population pharmacokinetics of intramuscular recombinant Erwinia chrysanthemi asparaginase (JZP458)...

Population pharmacokinetics of intramuscular recombinant Erwinia chrysanthemi asparaginase (JZP458)...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0d61066b2ac14669bf84f3b8ad46f8e0

Population pharmacokinetics of intramuscular recombinant Erwinia chrysanthemi asparaginase (JZP458) in patients with acute lymphoblastic leukemia

About this item

Full title

Population pharmacokinetics of intramuscular recombinant Erwinia chrysanthemi asparaginase (JZP458) in patients with acute lymphoblastic leukemia

Publisher

United States: John Wiley & Sons, Inc

Journal title

Clinical and translational science, 2023-05, Vol.16 (5), p.898-909

Language

English

Formats

Publication information

Publisher

United States: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

JZP458 is a recombinant Erwinia chrysanthemi asparaginase for patients with acute lymphoblastic leukemia (ALL)/lymphoblastic lymphoma (LBL) who have developed hypersensitivity to Escherichia coli–derived asparaginases. A population pharmacokinetic (PopPK) model was developed for intramuscular (i.m.) JZP458 using serum asparaginase activity (SAA) da...

Alternative Titles

Full title

Population pharmacokinetics of intramuscular recombinant Erwinia chrysanthemi asparaginase (JZP458) in patients with acute lymphoblastic leukemia

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_0d61066b2ac14669bf84f3b8ad46f8e0

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0d61066b2ac14669bf84f3b8ad46f8e0

Other Identifiers

ISSN

1752-8054,1752-8062

E-ISSN

1752-8062

DOI

10.1111/cts.13499

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