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Endothelial deletion of Ino80 disrupts coronary angiogenesis and causes congenital heart disease

Endothelial deletion of Ino80 disrupts coronary angiogenesis and causes congenital heart disease

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0d8c87a059fa43f486965f124732ed10

Endothelial deletion of Ino80 disrupts coronary angiogenesis and causes congenital heart disease

About this item

Full title

Endothelial deletion of Ino80 disrupts coronary angiogenesis and causes congenital heart disease

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2018-01, Vol.9 (1), p.368-16, Article 368

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

During development, the formation of a mature, well-functioning heart requires transformation of the ventricular wall from a loose trabecular network into a dense compact myocardium at mid-gestation. Failure to compact is associated in humans with congenital diseases such as left ventricular non-compaction (LVNC). The mechanisms regulating myocardi...

Alternative Titles

Full title

Endothelial deletion of Ino80 disrupts coronary angiogenesis and causes congenital heart disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_0d8c87a059fa43f486965f124732ed10

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0d8c87a059fa43f486965f124732ed10

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-017-02796-3

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