Rapid and ultra-sensitive quantitation of disease-associated α-synuclein seeds in brain and cerebros...
Rapid and ultra-sensitive quantitation of disease-associated α-synuclein seeds in brain and cerebrospinal fluid by αSyn RT-QuIC
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Publisher
England: BioMed Central
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Language
English
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Publisher
England: BioMed Central
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Contents
The diagnosis and treatment of synucleinopathies such as Parkinson disease and dementia with Lewy bodies would be aided by the availability of assays for the pathogenic disease-associated forms of α-synuclein (αSyn
) that are sufficiently sensitive, specific, and practical for analysis of accessible diagnostic specimens. Two recent αSyn
seed...
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Full title
Rapid and ultra-sensitive quantitation of disease-associated α-synuclein seeds in brain and cerebrospinal fluid by αSyn RT-QuIC
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TN_cdi_doaj_primary_oai_doaj_org_article_0d9bd34d07954635a1bb8e7f7cbb63e7
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0d9bd34d07954635a1bb8e7f7cbb63e7
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ISSN
2051-5960
E-ISSN
2051-5960
DOI
10.1186/s40478-018-0508-2
