ALDH1A1 provides a source of meiosis-inducing retinoic acid in mouse fetal ovaries
ALDH1A1 provides a source of meiosis-inducing retinoic acid in mouse fetal ovaries
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Substantial evidence exists that during fetal ovarian development in mammals, retinoic acid (RA) induces germ cells to express the pre-meiotic marker
Stra8
and enter meiosis, and that these effects are prevented in the fetal testis by the RA-degrading P450 enzyme CYP26B1. Nonetheless, the role of RA has been disputed principally because germ...
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ALDH1A1 provides a source of meiosis-inducing retinoic acid in mouse fetal ovaries
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TN_cdi_doaj_primary_oai_doaj_org_article_0e22b65b446446819a8346023e0c02d8
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0e22b65b446446819a8346023e0c02d8
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms10845
