Cocrystal of Apixaban–Quercetin: Improving Solubility and Bioavailability of Drug Combination of Two...
Cocrystal of Apixaban–Quercetin: Improving Solubility and Bioavailability of Drug Combination of Two Poorly Soluble Drugs
About this item
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Author / Creator
Zhang, Li , Kong, Dewen , Wang, Hongjuan , Jiao, Lingtai , Zhao, Xiaoyue , Song, Junke , Yang, Dezhi , Yang, Haiguang , Yang, Shiying , Du, Guanhua and Lu, Yang
Publisher
Basel: MDPI AG
Journal title
Language
English
Formats
Publication information
Publisher
Basel: MDPI AG
Subjects
More information
Scope and Contents
Contents
Drug combinations have been the hotspot of the pharmaceutical industry, but the promising applications are limited by the unmet solubility and low bioavailability. In this work, novel cocrystals, consisting of two antithrombotic drugs with poor solubility and low bioavailability in vivo, namely, apixaban (Apx) and quercetin (Que), were developed to...
Alternative Titles
Full title
Cocrystal of Apixaban–Quercetin: Improving Solubility and Bioavailability of Drug Combination of Two Poorly Soluble Drugs
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_0e26fb6fecdf471d86a1757578372894
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0e26fb6fecdf471d86a1757578372894
Other Identifiers
ISSN
1420-3049
E-ISSN
1420-3049
DOI
10.3390/molecules26092677
