Transcriptional profiling reveals a subset of human breast tumors that retain wt TP53 but display mu...
Transcriptional profiling reveals a subset of human breast tumors that retain wt TP53 but display mutant p53‐associated features
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United States: John Wiley & Sons, Inc
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English
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United States: John Wiley & Sons, Inc
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TP53 gene mutations are very common in human cancer. While such mutations abrogate the tumor suppressive activities of the wild‐type (wt) p53 protein, some of them also endow the mutant (mut) protein with oncogenic gain of function (GOF), facilitating cancer progression. Yet, p53 may acquire altered functionality even without being mutated; in part...
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Transcriptional profiling reveals a subset of human breast tumors that retain wt TP53 but display mutant p53‐associated features
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TN_cdi_doaj_primary_oai_doaj_org_article_0e3731e53bbb46d18432564f83817490
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0e3731e53bbb46d18432564f83817490
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ISSN
1574-7891,1878-0261
E-ISSN
1878-0261
DOI
10.1002/1878-0261.12736