Deep proteomic profiling unveils arylsulfatase A as a non-alcoholic steatohepatitis inducible hepato...
Deep proteomic profiling unveils arylsulfatase A as a non-alcoholic steatohepatitis inducible hepatokine and regulator of glycemic control
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Author / Creator
Montgomery, Magdalene K. , Bayliss, Jacqueline , Nie, Shuai , De Nardo, William , Keenan, Stacey N. , Miotto, Paula M. , Karimkhanloo, Hamzeh , Huang, Cheng , Schittenhelm, Ralf B. , Don, Anthony S. , Ryan, Andrew , Williamson, Nicholas A. , Ooi, Geraldine J. , Brown, Wendy A. , Burton, Paul R. , Parker, Benjamin L. and Watt, Matthew J.
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Non-alcoholic steatohepatitis (NASH) and type 2 diabetes are closely linked, yet the pathophysiological mechanisms underpinning this bidirectional relationship remain unresolved. Using proteomic approaches, we interrogate hepatocyte protein secretion in two models of murine NASH to understand how liver-derived factors modulate lipid metabolism and...
Alternative Titles
Full title
Deep proteomic profiling unveils arylsulfatase A as a non-alcoholic steatohepatitis inducible hepatokine and regulator of glycemic control
Authors, Artists and Contributors
Author / Creator
Bayliss, Jacqueline
Nie, Shuai
De Nardo, William
Keenan, Stacey N.
Miotto, Paula M.
Karimkhanloo, Hamzeh
Huang, Cheng
Schittenhelm, Ralf B.
Don, Anthony S.
Ryan, Andrew
Williamson, Nicholas A.
Ooi, Geraldine J.
Brown, Wendy A.
Burton, Paul R.
Parker, Benjamin L.
Watt, Matthew J.
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TN_cdi_doaj_primary_oai_doaj_org_article_0e3d36630f204b8aa3e526d0e0913eb1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0e3d36630f204b8aa3e526d0e0913eb1
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-28889-2