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A schizophrenia subgroup with elevated inflammation displays reduced microglia, increased peripheral...

A schizophrenia subgroup with elevated inflammation displays reduced microglia, increased peripheral...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0e77c55fa83748ecb0f9b24fd854d58e

A schizophrenia subgroup with elevated inflammation displays reduced microglia, increased peripheral immune cell and altered neurogenesis marker gene expression in the subependymal zone

About this item

Full title

A schizophrenia subgroup with elevated inflammation displays reduced microglia, increased peripheral immune cell and altered neurogenesis marker gene expression in the subependymal zone

Publisher

London: Nature Publishing Group UK

Journal title

Translational psychiatry, 2021-12, Vol.11 (1), p.635-635, Article 635

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Inflammation regulates neurogenesis, and the brains of patients with schizophrenia and bipolar disorder have reduced expression of neurogenesis markers in the subependymal zone (SEZ), the birthplace of inhibitory interneurons. Inflammation is associated with cortical interneuron deficits, but the relationship between inflammation and reduced neurog...

Alternative Titles

Full title

A schizophrenia subgroup with elevated inflammation displays reduced microglia, increased peripheral immune cell and altered neurogenesis marker gene expression in the subependymal zone

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_0e77c55fa83748ecb0f9b24fd854d58e

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0e77c55fa83748ecb0f9b24fd854d58e

Other Identifiers

ISSN

2158-3188

E-ISSN

2158-3188

DOI

10.1038/s41398-021-01742-8

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