Role of Glutamatergic Excitotoxicity in Neuromyelitis Optica Spectrum Disorders
Role of Glutamatergic Excitotoxicity in Neuromyelitis Optica Spectrum Disorders
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Switzerland: Frontiers Research Foundation
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Language
English
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Publisher
Switzerland: Frontiers Research Foundation
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Contents
Neuromyelitis optica spectrum disorder (NMOSD) is an inflammatory disorder mediated by immune-humoral responses directed against central nervous system (CNS) antigens. Most patients are positive for specific immunoglobulin G (IgG) auto-antibodies for aquaporin-4 (AQP4), a water channel present in astrocytes. Antigen-antibody binding promotes comple...
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Role of Glutamatergic Excitotoxicity in Neuromyelitis Optica Spectrum Disorders
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TN_cdi_doaj_primary_oai_doaj_org_article_0e80dc7f2dcd48bca805b35c5278e3b7
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0e80dc7f2dcd48bca805b35c5278e3b7
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ISSN
1662-5102
E-ISSN
1662-5102
DOI
10.3389/fncel.2019.00142
