Identifying inhibitors of β-haematin formation with activity against chloroquine-resistant Plasmodiu...
Identifying inhibitors of β-haematin formation with activity against chloroquine-resistant Plasmodium falciparum malaria parasites via virtual screening approaches
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
The biomineral haemozoin, or its synthetic analogue β-haematin (βH), has been the focus of several target-based screens for activity against
Plasmodium falciparum
parasites. Together with the known βH crystal structure, the availability of this screening data makes the target amenable to both structure-based and ligand-based virtual screening...
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Full title
Identifying inhibitors of β-haematin formation with activity against chloroquine-resistant Plasmodium falciparum malaria parasites via virtual screening approaches
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TN_cdi_doaj_primary_oai_doaj_org_article_0e9d9577f75f4ad3b7611cf98b1a8ed3
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0e9d9577f75f4ad3b7611cf98b1a8ed3
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-023-29273-w
