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Neurovascular unit disruption and blood–brain barrier leakage in MCT8 deficiency

Neurovascular unit disruption and blood–brain barrier leakage in MCT8 deficiency

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0eeb6dae8d194ee1ad7e04172c78f784

Neurovascular unit disruption and blood–brain barrier leakage in MCT8 deficiency

About this item

Full title

Neurovascular unit disruption and blood–brain barrier leakage in MCT8 deficiency

Publisher

London: BioMed Central Ltd

Journal title

Fluids and barriers of the CNS, 2023-11, Vol.20 (1), p.1-79, Article 79

Language

English

Formats

Publication information

Publisher

London: BioMed Central Ltd

More information

Scope and Contents

Contents

Background The monocarboxylate transporter 8 (MCT8) plays a vital role in maintaining brain thyroid hormone homeostasis. This transmembrane transporter is expressed at the brain barriers, as the blood-brain barrier (BBB), and in neural cells, being the sole known thyroid hormone-specific transporter to date. Inactivating mutations in the MCT8 gene...

Alternative Titles

Full title

Neurovascular unit disruption and blood–brain barrier leakage in MCT8 deficiency

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_0eeb6dae8d194ee1ad7e04172c78f784

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0eeb6dae8d194ee1ad7e04172c78f784

Other Identifiers

ISSN

2045-8118

E-ISSN

2045-8118

DOI

10.1186/s12987-023-00481-w

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