Neurovascular unit disruption and blood–brain barrier leakage in MCT8 deficiency
Neurovascular unit disruption and blood–brain barrier leakage in MCT8 deficiency
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London: BioMed Central Ltd
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English
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London: BioMed Central Ltd
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Background The monocarboxylate transporter 8 (MCT8) plays a vital role in maintaining brain thyroid hormone homeostasis. This transmembrane transporter is expressed at the brain barriers, as the blood-brain barrier (BBB), and in neural cells, being the sole known thyroid hormone-specific transporter to date. Inactivating mutations in the MCT8 gene...
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Neurovascular unit disruption and blood–brain barrier leakage in MCT8 deficiency
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TN_cdi_doaj_primary_oai_doaj_org_article_0eeb6dae8d194ee1ad7e04172c78f784
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0eeb6dae8d194ee1ad7e04172c78f784
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ISSN
2045-8118
E-ISSN
2045-8118
DOI
10.1186/s12987-023-00481-w