Lkb1 maintains Treg cell lineage identity
Lkb1 maintains Treg cell lineage identity
About this item
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Author / Creator
Wu, Di , Luo, Yuechen , Guo, Wei , Niu, Qing , Xue, Ting , Yang, Fei , Sun, Xiaolei , Chen, Song , Liu, Yuanyuan , Liu, Jingru , Sun, Zhina , Zhao, Chunxiao , Huang, Huifang , Liao, Fang , Han, Zhongchao , Zhou, Dongming , Yang, Yongguang , Xu, Guogang , Cheng, Tao and Feng, Xiaoming
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Regulatory T (T
reg
) cells are a distinct T-cell lineage characterized by sustained
Foxp3
expression and potent suppressor function, but the upstream dominant factors that preserve T
reg
lineage-specific features are mostly unknown. Here, we show that Lkb1 maintains T
reg
cell lineage identity by stabilizing
Foxp3
exp...
Alternative Titles
Full title
Lkb1 maintains Treg cell lineage identity
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_0ef92e5f9d09435488a06a64dac0a2a3
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0ef92e5f9d09435488a06a64dac0a2a3
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms15876
