EpCAM-dependent extracellular vesicles from intestinal epithelial cells maintain intestinal tract im...
EpCAM-dependent extracellular vesicles from intestinal epithelial cells maintain intestinal tract immune balance
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
How the intestinal tract develops a tolerance to foreign antigens is still largely unknown. Here we report that extracellular vesicles (EVs) with TGF-β1-dependent immunosuppressive activity are produced by intestinal epithelial cells (IECs) under physiological conditions. Transfer of these EVs into inflammatory bowel disease (IBD) mice induced by d...
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Full title
EpCAM-dependent extracellular vesicles from intestinal epithelial cells maintain intestinal tract immune balance
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TN_cdi_doaj_primary_oai_doaj_org_article_0f001c45d44d4449bc6667aedb702e5c
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0f001c45d44d4449bc6667aedb702e5c
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms13045
