MYC activation cooperates with Vhl and Ink4a/Arf loss to induce clear cell renal cell carcinoma
MYC activation cooperates with Vhl and Ink4a/Arf loss to induce clear cell renal cell carcinoma
About this item
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Author / Creator
Bailey, Sean T. , Smith, Aleisha M. , Kardos, Jordan , Wobker, Sara E. , Wilson, Harper L. , Krishnan, Bhavani , Saito, Ryoichi , Lee, Hyo Jin , Zhang, Jing , Eaton, Samuel C. , Williams, Lindsay A. , Manocha, Ujjawal , Peters, Dorien J. , Pan, Xinchao , Carroll, Thomas J. , Felsher, Dean W. , Walter, Vonn , Zhang, Qing , Parker, Joel S. , Yeh, Jen Jen , Moffitt, Richard A. , Leung, Janet Y. and Kim, William Y.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Renal carcinoma is a common and aggressive malignancy whose histopathogenesis is incompletely understood and that is largely resistant to cytotoxic chemotherapy. We present two mouse models of kidney cancer that recapitulate the genomic alterations found in human papillary (pRCC) and clear cell RCC (ccRCC), the most common RCC subtypes. MYC activat...
Alternative Titles
Full title
MYC activation cooperates with Vhl and Ink4a/Arf loss to induce clear cell renal cell carcinoma
Authors, Artists and Contributors
Author / Creator
Smith, Aleisha M.
Kardos, Jordan
Wobker, Sara E.
Wilson, Harper L.
Krishnan, Bhavani
Saito, Ryoichi
Lee, Hyo Jin
Zhang, Jing
Eaton, Samuel C.
Williams, Lindsay A.
Manocha, Ujjawal
Peters, Dorien J.
Pan, Xinchao
Carroll, Thomas J.
Felsher, Dean W.
Walter, Vonn
Zhang, Qing
Parker, Joel S.
Yeh, Jen Jen
Moffitt, Richard A.
Leung, Janet Y.
Kim, William Y.
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_0f0c33aaa830403a92bded52b464aea5
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0f0c33aaa830403a92bded52b464aea5
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms15770
