100 years of sickle cell disease research: etiology, pathophysiology and rational drug design (part...
100 years of sickle cell disease research: etiology, pathophysiology and rational drug design (part 1)
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Berlin/Heidelberg: Springer Berlin Heidelberg
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English
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Berlin/Heidelberg: Springer Berlin Heidelberg
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Background
Sickle cell disease (SCD) is a chronic hemolytic disease caused by an altered hemoglobin molecule (HbS) and was first termed as a molecular disease. Glutamic acid in the normal hemoglobin molecule (HbA), was replaced by valine in HbS at the sixth position of both β-chains. This alteration was proved to be due to a single point mutatio...
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100 years of sickle cell disease research: etiology, pathophysiology and rational drug design (part 1)
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TN_cdi_doaj_primary_oai_doaj_org_article_0f13586bff5a42288e638aa7cbfec1e7
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0f13586bff5a42288e638aa7cbfec1e7
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ISSN
2314-8543,2314-8535
E-ISSN
2314-8543
DOI
10.1186/s43088-019-0016-x
