BRCA locus-specific loss of heterozygosity in germline BRCA1 and BRCA2 carriers
BRCA locus-specific loss of heterozygosity in germline BRCA1 and BRCA2 carriers
About this item
Full title
Author / Creator
Maxwell, Kara N. , Wubbenhorst, Bradley , Wenz, Brandon M. , De Sloover, Daniel , Pluta, John , Emery, Lyndsey , Barrett, Amanda , Kraya, Adam A. , Anastopoulos, Ioannis N. , Yu, Shun , Jiang, Yuchao , Chen, Hao , Zhang, Nancy R. , Hackman, Nicole , D’Andrea, Kurt , Daber, Robert , Morrissette, Jennifer J. D. , Mitra, Nandita , Feldman, Michael , Domchek, Susan M. and Nathanson, Katherine L.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Complete loss of BRCA1 or BRCA2 function is associated with sensitivity to DNA damaging agents. However, not all
BRCA1
and
BRCA2
germline mutation-associated tumors respond. Herein we report analyses of 160
BRCA1
and
BRCA2
germline mutation-associated breast and ovarian tumors. Retention of the normal
BRCA1
or
BRCA2...
Alternative Titles
Full title
BRCA locus-specific loss of heterozygosity in germline BRCA1 and BRCA2 carriers
Authors, Artists and Contributors
Author / Creator
Wubbenhorst, Bradley
Wenz, Brandon M.
De Sloover, Daniel
Pluta, John
Emery, Lyndsey
Barrett, Amanda
Kraya, Adam A.
Anastopoulos, Ioannis N.
Yu, Shun
Jiang, Yuchao
Chen, Hao
Zhang, Nancy R.
Hackman, Nicole
D’Andrea, Kurt
Daber, Robert
Morrissette, Jennifer J. D.
Mitra, Nandita
Feldman, Michael
Domchek, Susan M.
Nathanson, Katherine L.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_0f6f94b247c0462089e5fb392de747ba
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0f6f94b247c0462089e5fb392de747ba
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-017-00388-9
