CAF secreted miR-522 suppresses ferroptosis and promotes acquired chemo-resistance in gastric cancer
CAF secreted miR-522 suppresses ferroptosis and promotes acquired chemo-resistance in gastric cancer
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Author / Creator
Zhang, Haiyang , Deng, Ting , Liu, Rui , Ning, Tao , Yang, Haiou , Liu, Dongying , Zhang, Qiumo , Lin, Dan , Ge, Shaohua , Bai, Ming , Wang, Xinyi , Zhang, Le , Li, Hongli , Yang, Yuchong , Ji, Zhi , Wang, Hailong , Ying, Guoguang and Ba, Yi
Publisher
England: BioMed Central Ltd
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English
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Publisher
England: BioMed Central Ltd
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Contents
Ferroptosis is a novel mode of non-apoptotic cell death induced by build-up of toxic lipid peroxides (lipid-ROS) in an iron dependent manner. Cancer-associated fibroblasts (CAFs) support tumor progression and drug resistance by secreting various bioactive substances, including exosomes. Yet, the role of CAFs in regulating lipid metabolism as well a...
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Full title
CAF secreted miR-522 suppresses ferroptosis and promotes acquired chemo-resistance in gastric cancer
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TN_cdi_doaj_primary_oai_doaj_org_article_0f7fec71076041c089b993d3f0940378
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0f7fec71076041c089b993d3f0940378
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ISSN
1476-4598
E-ISSN
1476-4598
DOI
10.1186/s12943-020-01168-8
