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A natural PKM2 targeting agent as a potential drug for breast cancer treatment

A natural PKM2 targeting agent as a potential drug for breast cancer treatment

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0f8076d2d9e143ca8fa09beadc2786b5

A natural PKM2 targeting agent as a potential drug for breast cancer treatment

About this item

Full title

A natural PKM2 targeting agent as a potential drug for breast cancer treatment

Publisher

United States: John Wiley & Sons, Inc

Journal title

Clinical and Translational Medicine, 2023-01, Vol.13 (1), p.e1157-n/a

Language

English

Formats

Publication information

Publisher

United States: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

The results showed a concentration-dependent decrease in the viability of breast cancer cells after treatment with YHC (Figure S1A–C). [...]YHC was less toxic than positive controls (Dox and Tam) on human normal breast epithelial cells MCF-10A cells (Figure S2). A peak corresponding to pyruvate kinase M2 (PKM2) was identified by mass spectrometry,...

Alternative Titles

Full title

A natural PKM2 targeting agent as a potential drug for breast cancer treatment

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_0f8076d2d9e143ca8fa09beadc2786b5

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0f8076d2d9e143ca8fa09beadc2786b5

Other Identifiers

ISSN

2001-1326

E-ISSN

2001-1326

DOI

10.1002/ctm2.1157

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