Exosomes derived from pancreatic cancer cells induce insulin resistance in C2C12 myotube cells throu...
Exosomes derived from pancreatic cancer cells induce insulin resistance in C2C12 myotube cells through the PI3K/Akt/FoxO1 pathway
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Author / Creator
Wang, Lantian , Zhang, Bo , Zheng, Wen , Kang, Muxing , Chen, Qing , Qin, Wenjie , Li, Chao , Zhang, Yuefeng , Shao, Yingkuan and Wu, Yulian
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Prospective epidemiological studies have consistently suggested that pancreatic cancer-associated new-onset diabetes mellitus (PC-DM) represents a potential platform for early diagnose of pancreatic cancer (PC). Despite the studies performed, the mechanism behind this phenomenon remains ambiguous. In this study, we explored the effects of two types...
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Full title
Exosomes derived from pancreatic cancer cells induce insulin resistance in C2C12 myotube cells through the PI3K/Akt/FoxO1 pathway
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TN_cdi_doaj_primary_oai_doaj_org_article_0f8322d09eb54f27b10a6e8a3ed44ba6
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0f8322d09eb54f27b10a6e8a3ed44ba6
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-017-05541-4