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Assessing CD36 and CD47 expression levels in solid tumor indications to stratify patients for VT1021...

Assessing CD36 and CD47 expression levels in solid tumor indications to stratify patients for VT1021...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0f96566457eb478681a046ba79ade1bd

Assessing CD36 and CD47 expression levels in solid tumor indications to stratify patients for VT1021 treatment

About this item

Full title

Assessing CD36 and CD47 expression levels in solid tumor indications to stratify patients for VT1021 treatment

Publisher

London: Nature Publishing Group UK

Journal title

NPJ precision oncology, 2024-12, Vol.8 (1), p.278-10, Article 278

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Despite the development of cancer biomarkers and targeted therapies, most cancer patients do not have a specific biomarker directly associated with effective treatment options. We have developed VT1021 that induces the expression of thrombospondin-1 (TSP-1) in myeloid-derived suppressor cells (MDSCs) recruited to the tumor microenvironment (TME). O...

Alternative Titles

Full title

Assessing CD36 and CD47 expression levels in solid tumor indications to stratify patients for VT1021 treatment

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_0f96566457eb478681a046ba79ade1bd

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0f96566457eb478681a046ba79ade1bd

Other Identifiers

ISSN

2397-768X

E-ISSN

2397-768X

DOI

10.1038/s41698-024-00774-9

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