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Constitutive hippocampal cholesterol loss underlies poor cognition in old rodents

Constitutive hippocampal cholesterol loss underlies poor cognition in old rodents

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0f969627a175411abeabdd5cb072e280

Constitutive hippocampal cholesterol loss underlies poor cognition in old rodents

About this item

Full title

Constitutive hippocampal cholesterol loss underlies poor cognition in old rodents

Publisher

London: Nature Publishing Group UK

Journal title

EMBO molecular medicine, 2014-07, Vol.6 (7), p.902-917

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Cognitive decline is one of the many characteristics of aging. Reduced long‐term potentiation (LTP) and long‐term depression (LTD) are thought to be responsible for this decline, although the precise mechanisms underlying LTP and LTD dampening in the old remain unclear. We previously showed that aging is accompanied by the loss of cholesterol from...

Alternative Titles

Full title

Constitutive hippocampal cholesterol loss underlies poor cognition in old rodents

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_0f969627a175411abeabdd5cb072e280

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0f969627a175411abeabdd5cb072e280

Other Identifiers

ISSN

1757-4676

E-ISSN

1757-4684

DOI

10.15252/emmm.201303711

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