Constitutive hippocampal cholesterol loss underlies poor cognition in old rodents
Constitutive hippocampal cholesterol loss underlies poor cognition in old rodents
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Cognitive decline is one of the many characteristics of aging. Reduced long‐term potentiation (LTP) and long‐term depression (LTD) are thought to be responsible for this decline, although the precise mechanisms underlying LTP and LTD dampening in the old remain unclear. We previously showed that aging is accompanied by the loss of cholesterol from...
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Constitutive hippocampal cholesterol loss underlies poor cognition in old rodents
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TN_cdi_doaj_primary_oai_doaj_org_article_0f969627a175411abeabdd5cb072e280
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0f969627a175411abeabdd5cb072e280
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1757-4676
E-ISSN
1757-4684
DOI
10.15252/emmm.201303711