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Treatment with senicapoc in a porcine model of acute respiratory distress syndrome

Treatment with senicapoc in a porcine model of acute respiratory distress syndrome

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0f96c432b6844668824cc00292f1418f

Treatment with senicapoc in a porcine model of acute respiratory distress syndrome

About this item

Full title

Treatment with senicapoc in a porcine model of acute respiratory distress syndrome

Publisher

Cham: Springer International Publishing

Journal title

Intensive Care Medicine Experimental, 2021-04, Vol.9 (1), p.20-20, Article 20

Language

English

Formats

Publication information

Publisher

Cham: Springer International Publishing

More information

Scope and Contents

Contents

Background
Senicapoc is a potent and selective blocker of KCa3.1, a calcium-activated potassium channel of intermediate conductance. In the present study, we investigated whether there is a beneficial effect of senicapoc in a large animal model of acute respiratory distress syndrome (ARDS). The primary end point was the PaO
2
/FiO
2
...

Alternative Titles

Full title

Treatment with senicapoc in a porcine model of acute respiratory distress syndrome

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_0f96c432b6844668824cc00292f1418f

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0f96c432b6844668824cc00292f1418f

Other Identifiers

ISSN

2197-425X

E-ISSN

2197-425X

DOI

10.1186/s40635-021-00381-z

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