Treatment with senicapoc in a porcine model of acute respiratory distress syndrome
Treatment with senicapoc in a porcine model of acute respiratory distress syndrome
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Cham: Springer International Publishing
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Language
English
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Cham: Springer International Publishing
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Background
Senicapoc is a potent and selective blocker of KCa3.1, a calcium-activated potassium channel of intermediate conductance. In the present study, we investigated whether there is a beneficial effect of senicapoc in a large animal model of acute respiratory distress syndrome (ARDS). The primary end point was the PaO
2
/FiO
2
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Full title
Treatment with senicapoc in a porcine model of acute respiratory distress syndrome
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TN_cdi_doaj_primary_oai_doaj_org_article_0f96c432b6844668824cc00292f1418f
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0f96c432b6844668824cc00292f1418f
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ISSN
2197-425X
E-ISSN
2197-425X
DOI
10.1186/s40635-021-00381-z