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Alevin efficiently estimates accurate gene abundances from dscRNA-seq data

Alevin efficiently estimates accurate gene abundances from dscRNA-seq data

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0fd3e361ed254020a5219a3e4163d9e4

Alevin efficiently estimates accurate gene abundances from dscRNA-seq data

About this item

Full title

Alevin efficiently estimates accurate gene abundances from dscRNA-seq data

Publisher

England: BioMed Central

Journal title

Genome Biology, 2019-03, Vol.20 (1), p.65-65, Article 65

Language

English

Formats

Publication information

Publisher

England: BioMed Central

More information

Scope and Contents

Contents

We introduce alevin, a fast end-to-end pipeline to process droplet-based single-cell RNA sequencing data, performing cell barcode detection, read mapping, unique molecular identifier (UMI) deduplication, gene count estimation, and cell barcode whitelisting. Alevin's approach to UMI deduplication considers transcript-level constraints on the molecul...

Alternative Titles

Full title

Alevin efficiently estimates accurate gene abundances from dscRNA-seq data

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_0fd3e361ed254020a5219a3e4163d9e4

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0fd3e361ed254020a5219a3e4163d9e4

Other Identifiers

ISSN

1474-760X,1474-7596

E-ISSN

1474-760X

DOI

10.1186/s13059-019-1670-y

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