Orexin neurons inhibit sleep to promote arousal
Orexin neurons inhibit sleep to promote arousal
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Author / Creator
De Luca, Roberto , Nardone, Stefano , Grace, Kevin P. , Venner, Anne , Cristofolini, Michela , Bandaru, Sathyajit S. , Sohn, Lauren T. , Kong, Dong , Mochizuki, Takatoshi , Viberti, Bianca , Zhu, Lin , Zito, Antonino , Scammell, Thomas E. , Saper, Clifford B. , Lowell, Bradford B. , Fuller, Patrick M. and Arrigoni, Elda
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Humans and animals lacking orexin neurons exhibit daytime sleepiness, sleep attacks, and state instability. While the circuit basis by which orexin neurons contribute to consolidated wakefulness remains unclear, existing models posit that orexin neurons provide their wake-stabilizing influence by exerting excitatory tone on other brain arousal node...
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Orexin neurons inhibit sleep to promote arousal
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TN_cdi_doaj_primary_oai_doaj_org_article_0fd72beca5ba4c64b5cd0f002371285b
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0fd72beca5ba4c64b5cd0f002371285b
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-31591-y