KL-VS heterozygosity is associated with lower amyloid-dependent tau accumulation and memory impairme...
KL-VS heterozygosity is associated with lower amyloid-dependent tau accumulation and memory impairment in Alzheimer’s disease
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Klotho-VS heterozygosity (KL-VS
het
) is associated with reduced risk of Alzheimer’s disease (AD). However, whether KL-VS
het
is associated with lower levels of pathologic tau, i.e., the key AD pathology driving neurodegeneration and cognitive decline, is unknown. Here, we assessed the interaction between KL-VS
het
and levels of b...
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Full title
KL-VS heterozygosity is associated with lower amyloid-dependent tau accumulation and memory impairment in Alzheimer’s disease
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TN_cdi_doaj_primary_oai_doaj_org_article_0ffe3664dd584e458ee1ba0a49270e64
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_0ffe3664dd584e458ee1ba0a49270e64
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-23755-z
