Pathway of Hsp70 interactions at the ribosome
Pathway of Hsp70 interactions at the ribosome
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
In eukaryotes, an Hsp70 molecular chaperone triad assists folding of nascent chains emerging from the ribosome tunnel. In fungi, the triad consists of canonical Hsp70 Ssb, atypical Hsp70 Ssz1 and J-domain protein cochaperone Zuo1. Zuo1 binds the ribosome at the tunnel exit. Zuo1 also binds Ssz1, tethering it to the ribosome, while its J-domain stim...
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Full title
Pathway of Hsp70 interactions at the ribosome
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TN_cdi_doaj_primary_oai_doaj_org_article_101d4b2643d04db4b8351919b8a8bf11
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_101d4b2643d04db4b8351919b8a8bf11
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-25930-8
