The MICA‐129 dimorphism affects NKG2D signaling and outcome of hematopoietic stem cell transplantati...
The MICA‐129 dimorphism affects NKG2D signaling and outcome of hematopoietic stem cell transplantation
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Isernhagen, Antje , Malzahn, Dörthe , Viktorova, Elena , Elsner, Leslie , Monecke, Sebastian , von Bonin, Frederike , Kilisch, Markus , Wermuth, Janne Marieke , Walther, Neele , Balavarca, Yesilda , Stahl‐Hennig, Christiane , Engelke, Michael , Walter, Lutz , Bickeböller, Heike , Kube, Dieter , Wulf, Gerald and Dressel, Ralf
Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
The MHC class I chain‐related molecule A (MICA) is a highly polymorphic ligand for the activating natural killer (NK)‐cell receptor NKG2D. A single nucleotide polymorphism causes a valine to methionine exchange at position 129. Presence of a
MICA‐129Met
allele in patients (
n
= 452) undergoing hematopoietic stem cell transplantation (H...
Alternative Titles
Full title
The MICA‐129 dimorphism affects NKG2D signaling and outcome of hematopoietic stem cell transplantation
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TN_cdi_doaj_primary_oai_doaj_org_article_10306a23c43f40c0b4441e4d3a488884
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_10306a23c43f40c0b4441e4d3a488884
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ISSN
1757-4676
E-ISSN
1757-4684
DOI
10.15252/emmm.201505246