Impairment of IGF2 gene expression in prostate cancer is triggered by epigenetic dysregulation of IG...
Impairment of IGF2 gene expression in prostate cancer is triggered by epigenetic dysregulation of IGF2-DMR0 and its interaction with KLF4
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England: BioMed Central
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English
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England: BioMed Central
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Human cancer cells often exhibit impaired IGF2 expression and the underlying mechanisms are multifaceted and complex. Besides the well-known imprinting control region IGF2/H19-ICR, the involvement of a differentially methylated region in the promoter P0 of IGF2 gene (IGF2-DMR0) has been suggested. Here, we evaluate several mechanisms potentially le...
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Full title
Impairment of IGF2 gene expression in prostate cancer is triggered by epigenetic dysregulation of IGF2-DMR0 and its interaction with KLF4
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TN_cdi_doaj_primary_oai_doaj_org_article_104d1d67a6c94062a0cd74925f8427cb
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_104d1d67a6c94062a0cd74925f8427cb
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ISSN
1478-811X
E-ISSN
1478-811X
DOI
10.1186/s12964-017-0197-7
