Durvalumab with or without tremelimumab combined with particle therapy for advanced hepatocellular c...
Durvalumab with or without tremelimumab combined with particle therapy for advanced hepatocellular carcinoma with macrovascular invasion: protocol for the DEPARTURE phase Ib trial
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Author / Creator
Ogasawara, Sadahisa , Koroki, Keisuke , Makishima, Hirokazu , Wakatsuki, Masaru , Takahashi, Asahi , Yumita, Sae , Nakagawa, Miyuki , Ishino, Takamasa , Ogawa, Keita , Fujiwara, Kisako , Iwanaga, Terunao , Sakuma, Takafumi , Fujita, Naoto , Kojima, Ryuta , Kanzaki, Hiroaki , Kobayashi, Kazufumi , Kiyono, Soichiro , Nakamura, Masato , Kanogawa, Naoya , Saito, Tomoko , Kondo, Takayuki , Nakagawa, Ryo , Nakamoto, Shingo , Muroyama, Ryosuke , Chiba, Tetsuhiro , Ozawa, Yoshihito , Kawasaki, Yohei , Kurokawa, Tomoya , Hanaoka, Hideki , Tsuji, Hiroshi and Kato, Naoya
Publisher
England: British Medical Journal Publishing Group
Journal title
Language
English
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Publication information
Publisher
England: British Medical Journal Publishing Group
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More information
Scope and Contents
Contents
IntroductionAdvanced hepatocellular carcinoma (HCC) with macrovascular invasion (MVI) has the worst prognosis among all phenotypes. This trial aims to evaluate whether treatment with durvalumab, alone or in combination with tremelimumab, plus particle therapy is a safe and synergistically effective treatment in patients with advanced HCC and MVI.Me...
Alternative Titles
Full title
Durvalumab with or without tremelimumab combined with particle therapy for advanced hepatocellular carcinoma with macrovascular invasion: protocol for the DEPARTURE phase Ib trial
Authors, Artists and Contributors
Author / Creator
Koroki, Keisuke
Makishima, Hirokazu
Wakatsuki, Masaru
Takahashi, Asahi
Yumita, Sae
Nakagawa, Miyuki
Ishino, Takamasa
Ogawa, Keita
Fujiwara, Kisako
Iwanaga, Terunao
Sakuma, Takafumi
Fujita, Naoto
Kojima, Ryuta
Kanzaki, Hiroaki
Kobayashi, Kazufumi
Kiyono, Soichiro
Nakamura, Masato
Kanogawa, Naoya
Saito, Tomoko
Kondo, Takayuki
Nakagawa, Ryo
Nakamoto, Shingo
Muroyama, Ryosuke
Chiba, Tetsuhiro
Ozawa, Yoshihito
Kawasaki, Yohei
Kurokawa, Tomoya
Hanaoka, Hideki
Tsuji, Hiroshi
Kato, Naoya
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_10cba6c799024b70a6436dd19587d4d4
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_10cba6c799024b70a6436dd19587d4d4
Other Identifiers
ISSN
2044-6055
E-ISSN
2044-6055
DOI
10.1136/bmjopen-2021-059779
